Causal analyses to identify risk factors for dementia Lead Investigator: Marie-Abele Bind Institution : Harvard University E-Mail : ma.bind@mail.harvard.edu Proposal ID : 1250 Proposal Description: Critical statistical barriers in epidemiology limit the field?s progression. There is a need to eliminate these barriers by incorporating statistical and causal methods. We will apply a four-stage causal strategy (Bind and Rubin, 2017) to identify risk factors for dementia. Using non-randomized studies, we are statistically equipped to determine causal relationships and rigorously estimate the joint, independent, and interactive effects of multiple risk factors on dementia.